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A master's thesis from Aalborg University
Book cover


The Multidimensional Burden of Pain Across Icelandic Cancer Survivors

Authors

;

Term

4. Term

Publication year

2026

Submitted on

Abstract

This thesis explores the multidimensional burden of pain among cancer survivors in Iceland at a time of rapidly increasing survivorship. Despite advances in detection and treatment, Icelandic cancer survivors experience a clinically meaningful excess pain burden compared with the general population, and previous work has shown that interference of pain with daily life is a key difference between survivors and controls. In this population-based cross-sectional study, conducted within the national Surv-Ice project, data from 3,585 adults who had completed cancer treatment were analyzed to understand why some survivors experience greater pain burden than others. Pain burden was assessed with the QLQ-SURV100, selected quality-of-life domains included role functioning, health distress, cognitive functioning and financial difficulties, health literacy was measured with the HLS-EU-Q16, and assistance-related needs were captured using an eight-item needs assessment questionnaire. Using linear regression models and correlation analyses, the study examined how these factors predict pain burden. Role functioning emerged as the strongest independent predictor, followed by health distress, cognitive functioning and financial difficulties, and together these quality-of-life domains explained about half of the variance in pain burden. Lower health literacy was associated with higher pain burden, and assistance needs related to physical symptoms and daily activities showed the strongest links to greater pain. The findings support understanding pain among Icelandic cancer survivors as a complex biopsychosocial outcome closely tied to functional ability, psychological and cognitive strain, financial stress, health literacy, and support needs. The thesis thereby highlights the importance of interdisciplinary survivorship care that addresses functional, psychosocial, socioeconomic and information-related factors to reduce the burden of pain in this growing patient group.

Denne afhandling undersøger den multidimensionelle byrde af smerter blandt kræftoverlevere i Island i en tid med markant stigende kræftoverlevelse. På trods af forbedret behandling har islandske kræftoverlevere en klinisk betydelig større smertebyrde end befolkningen generelt, og tidligere forskning har vist, at især smerters indvirkning på dagligdagen adskiller overlevere fra kontrolgruppen. I dette populationsbaserede tværsnitsstudie, gennemført som en del af det nationale Surv-Ice projekt, analyseres data fra 3.585 voksne, der har afsluttet kræftbehandling, for at belyse, hvorfor nogle overlevere oplever større smertebyrde end andre. Smertebyrde blev målt med QLQ-SURV100, udvalgte livskvalitetsdomæner omfattede rollefunktion, helbredsbekymring, kognitiv funktion og økonomiske vanskeligheder, sundhedskompetence blev vurderet med HLS-EU-Q16, og hjælperelaterede behov blev målt med et otte-items behovsskema. Ved hjælp af lineære regressionsmodeller og korrelationsanalyser blev det undersøgt, hvordan disse faktorer forudsiger smertebyrden. Rollefunktion viste sig at være den stærkeste uafhængige prædiktor, efterfulgt af helbredsbekymring, kognitiv funktion og økonomiske vanskeligheder, og disse livskvalitetsdomæner forklarede tilsammen omkring halvdelen af variationen i smertebyrde. Lavere sundhedskompetence var forbundet med højere smertebyrde, og behov for hjælp med fysiske symptomer og daglige aktiviteter havde de tydeligste sammenhænge med mere smerte. Resultaterne understøtter, at smerte blandt islandske kræftoverlevere bedst forstås som et komplekst biopsykosocialt fænomen, der hænger tæt sammen med funktionsevne, psykologisk og kognitiv belastning, økonomisk pres, sundhedskompetence og behov for støtte. Afhandlingen peger dermed på behovet for tværfaglig senfølge- og opfølgningsindsats, der både adresserer funktionelle, psykosociale, socioøkonomiske og informationsrelaterede faktorer for at reducere smertebyrden i denne voksende patientgruppe.

[This abstract has been generated with the help of AI directly from the project full text]