A class II hybrid, by the Sol-Gelroute for tissue engineering.
Translated title
A class II hybrid, by the Sol-Gelroute for tissue engineering
Author
Galsgaard, Mikkel Sjørslev
Term
4. term
Education
Publication year
2021
Submitted on
2021-12-31
Pages
43
Abstract
Denne afhandling, udarbejdet ved Aalborg Universitet fra februar til december 2021 af Mikkel S. Galsgaard, undersøger klasse II-hybridmaterialer—kombinationer af silica og poly(methacrylsyre), der er kemisk sammenkoblet. To sammenkoblingsmidler, GPTMS og TMSPMA, blev brugt til at forbinde den uorganiske og organiske del i forskellige blandingsforhold. Hvert materiale og de tilhørende referencer blev analyseret med FTIR-spektroskopi (til at bekræfte kemiske bindinger), termogravimetrisk analyse (TGA), nedbrydningstests, scanningelektronmikroskopi (SEM) og mikroindentering (til at vurdere overfladestruktur og mekaniske egenskaber). Analyserne havde til formål at kontrollere, at referencematerialerne var korrekt syntetiseret, og at vurdere, om nogle af hybridmaterialerne kunne være egnede som vævsingeniørmaterialer til knogletransplantater.
This thesis, completed at Aalborg University from February to December 2021 by Mikkel S. Galsgaard, investigates class II hybrid materials—combinations of silica and poly(methacrylic acid) that are chemically linked. Two coupling agents, GPTMS and TMSPMA, were used to connect the inorganic and organic parts at different mixing ratios. Each material and its reference samples were examined using FTIR spectroscopy (to confirm chemical bonds), thermogravimetric analysis (TGA), degradation testing, scanning electron microscopy (SEM), and micro-indentation (to assess surface structure and mechanical properties). These analyses were used to verify that the reference materials were synthesized correctly and to evaluate whether any of the hybrids could be suitable as tissue engineering materials for bone grafts.
[This summary has been rewritten with the help of AI based on the project's original abstract]
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