The forthcoming thesis surrounds the circumstances surrounding the notions of the motives behind the Denmark-Expedition 1906-1908. This expedition, lead by a certain Ludvig Mylius-Erichsen (1872-1907), was set to be the most comprehensive of its kind in Danish history. With him, he brought along several scientists, whose task it was to investigate Greenland in depth. This thesis surrounds three motives for this expedition; the nationalistic/imperial motives, the scientific motives and the economical motives. The prior decades leading up to this expedition, had seen both Norwegian and American presence in Greenland. The foreign activity in an imperialistic world, saw Denmark under external political pressure. The American presence was to become the most significant motive for this expedition. The prior decades had also seen a major advance in science. Through the notions of new sciences, the Danish presence in Greenland was to be solidified once and for all. However, was this notion of big science just a legitimate motive for imperialism, or was this aspect of science really a matter of political interest in Greenland; and, why did this expedition become so hugely important? Denmark sought to withstand the colony, as an economical one, and thus, Greenland became the most significant aspect of Danish foreign policy.