• Helene Dam Nielsen
  • Cecilie Mørk Brandsborg
  • Sine Nordstrøm Lambert Andersen
Introduction & aim: During assessment and treatment of acute myeloid leukemia for children and juvenile zero to 18 years, several blood samples, clinical examinations, and bone marrow samples are performed. This results in many registrations in the patient's electronic health record. These registrations can be made by different health professionals in different departments in different regions. There is thus a need to be able to reuse data registered by the responsible department in a supporting department and conversely. The aim of the study is therefore to accommodate this need through seamless interoperability. 
Method: The use of the Hevner Framework and Requirements Engineering enabled the development of an artefact based on the needs collected in two interviews and a literature search. Data in the artefact was standardized. The use of Requirements Engineering supported the artefact's design, development, and validation in its phases. The artefact was developed in Forge R4 (v. 4.0.1).
Results: The artefact consists of 12 profiles and one extension from HL7 FHIR. The artefact uses the semantic standards SNOMED CT, LOINC and ICD-10. The use of the technical and semantic standards ensures the potential for seamless interoperability. The artefact contains metadata about the healthcare professionals, which is an essential and innovative contribution in the electronic health record to achieve seamless interoperability. The artefact is validated using the ISO-standard 13606:2019. The profiles and the extension constitute a prototype that is instantiated using data from a theoretical case about the treatment of a patient with acute myeloid leukemia and registrations regarding the treatment. Furthermore, the profiles are uploaded to Simplifier.net where the validation is successful. To illustrate the reuse of data, visual prototypes are made containing data from the case and electronic health records.
Conclusion: It can be concluded that the implementation of the developed artefact with international standards and metadata facilitates the possibility for seamless interoperability. This is achieved by the reuse of data for a patient with acute myeloid leukemia. The implementation of the artefact increases national specialization in the assessment and treatment of acute myeloid leukemia.
Publication date1 Jun 2021
Number of pages165
ID: 413415411