• Kasper Mørk
  • Rana Baban
5. Term (Master thesis), Medicine, Master (Master Programme)
Background and objectives: Mitral regurgitation (MR) is the second most common valve disease, and it is increasingly treated with mitral valve repair e.g., Alfieri repair in favour of valve replacement. In this study, short term results after an Alfieri repair from Aalborg University Hospital are compared with international results. Methods: Pre-, peri- and post-operative data were collected from patients receiving an Alfieri repair between September 2015 and September 2020. Data were collected from the Western Danish Heart Registry and the electronic patient records. A descriptive statistical analysis was performed on all data and a paired t-test was used when comparing pre- and post-operative results with a level of significance at p<0.05. Mortality rate was determined using a Kaplan-Meier estimate. Results: A total of 43 patients were included in this study and all had moderate (7.0%) to severe (93.0%) MR caused by myxomatous degeneration. Mean age was 70.91 years (± 7.82), 22 patients (51.2%) had a NYHA score of I or II and 38 patients (88.4%) had comorbidities, most commonly hypertension (60.5%) and AF (58.1%). A total of 53.5% had postoperative complications, most commonly AF (32.6%). Postoperatively only three patients (7.0%) had residual MR, and 90.5% had NYHA I or II. Freedom of reoperation was 95.3% and readmission within 30 days was 14.0%. Conclusion: The short term results at the Department of Cardiothoracic Surgery, Aalborg University Hospital, Denmark, concerning mortality, occurrence of reoperation and readmission within 30 days after Alfieri repair is similar to those reported in international studies. However, a longer follow-up period, larger study population and five-year post-operative clinical follow-up, is to be desired for more precise and long-term results.
Publication date5 Jan 2021
Number of pages19
ID: 398122909