• Julie Friis Pedersen
  • Simone Høstgaard
5. Term (Master thesis), Medicine, Master (Master Programme)
Introduction: In Denmark, patients with rheumatologic diseases have assessed patient-reported outcome measures (PROMs) via a touchscreen prior to each consultation in the outpatient clinic since 2006; however, as technology develops, interest in new ways of collecting PROMs is emerging. Bring your own device (BYOD) is a relatively new way of collecting PROMs through a personal electronic device. This study is evaluating the comparability between the national Danish Rheumatology Database (DANBIO) web app through a smartphone or a tablet and the traditional outpatient touchscreen regarding patients with Systemic Lupus Erythematosus (SLE).
Objectives: the aim of the study is to compare the outpatient touchscreen to a from home web app with Systemic Lupus Activity Questionnaire (SLAQ) global health as primary outcome.
Methods: This is a randomized, within-participants crossover, agreement study with enrolment of patients with SLE. Participants were randomized into two groups assessing PROMs through the two devices in a randomized order with a predefined wash out period. Differences in PROM scores with 95% confidence intervals (CI) were evaluated for similarity according to prespecified equivalence margins and a Bland-Altman plot was used to assess limits of agreement.
Results: Equivalence was found for SLAQ global health with a difference between the two electronic devices of -0.21, 95% CI (-0.64 to 0.23); Furthermore, all other PROMs were equivalent except for Visual Analogue Scale (VAS) global as the 95% CI of -1.45 to 6.80 exceeded the equivalence margin of ± 5. However, the difference was well within the minimal clinically important difference (MCID) of ± 10. Thirty-one (91.2%) of the total 34 participants preferred the DANBIO web app.
Conclusion: For the first time in patients with SLE, comparability between PROMs collected on a web app and an outpatient touchscreen was verified. Participants highly preferred the DANBIO web-app. Thus, the future implementation of the DANBIO web-app is expected to be a helpful and valuable tool for both patients and health care in order to monitor patients on a more individualized level.
Publication date2021
Number of pages17
ID: 398401387