This thesis sought to investigate the optimal configuration for vortex generators (VG’s) for increase of performance in fin and tube heat exchangers. This was done with a conjugate heat transfer CFD model and numerical optimisation based on a surrogate model and a genetic algorithm. A total of five parameters were investigated: Angle of attack, VG -length and height and x - and y-coordinates of the VG’s relative to the tube centre. The numerical optimisation produced a configuration, that yielded a heat transfer increase of ≈ 24% with a pressure drop increase ≈ 7% in comparison to a plain fin geometry. The new configuration was compared with results from the CFD model. The CFD model showed that the optimisation had a deviation of 1.91% on the loss coefficient and 0.06% of the Nusselt number.