The project revolves around the design of an asylum centre. The process behind the final architectural design is subdivided into two phases, firstly; an assessment of architectures correlation with the health and well-being. Inquiry on this correlation was performed through assessments on the neurological- and psychological underpinnings of architectural preference and a corresponding examination of the state of the art review of the literature and empirical findings on architectures correlation with preference and emotional modulation. The first phase also included an assessment of the health and well-being of asylum-seekers applying for refugee status in the European nation. This inquiry displayed post-traumatic stress disorder as a wide spread mental issues among the designated user group of the architectural project. The assessment of the neurological- and psychological underpinnings of architectural preference and the findings on the topic, were correlated with neurological- and psychological abnormalities of post-traumatic stress disorder to extract user specific design guidelines for the implementation in the design of the asylum center. The second phase includes the design of a site specific asylum centre, positioned in ‘Hammer bakker’. The design process and inquiry for the project includes considerations on trinity of sustainability. These considerations were included in combination with the extract design guidelines from the first phase; resulting in an energy efficient architectural design with low environmental impact. The spatial configuration of the asylum center were designed according to the findings of phase one, therefore, theoretically, improving the treatment efficiency of post-traumatic stress disorder and generally improves the health and well-being of the center occupants through architectural interventions.