The purpose of this study was to investigate the field of evidence-based design used in architectural design practice to be able to propose a method using the software application Rhinoceros 3D with plugin Grasshopper to 1) enhance the integration of evidence based design knowledge in the early sketching phase and 2) to assess fulfilment of evidence based design criterion regarding patient safety in a design proposal. The study was based on both quantitative and qualitative methods. Throughout this study qualitative interviews with architectural employees and healthcare personnel were conducted. This to examine the relations between evidence-based design concepts in the design proposal, with the output performance of the built facilities. Scenario models were designed in correlation with architects to specify potentials, needs and demands regarding the development of the method. The study used parametric 2D/3D CAD modelling to create tool prototypes to exemplify the operations and functions that a future method might hold. To evaluate the prototype potentials, surveys with the architects were conducted with focus on a cognitive walkthrough of the tools. To retrieve specific information of evaluative character, quantitative questionnaires have been administered and used in development of the tools. The project has used results from 2 surveys with 9 individual respondents. A total of 18 questionnaires have been sent out where 10 questionnaires were answered. The results of the study were that the potentials of a software based design tool are significant and that architects recon the project prototypes as a meaningful and valuable approach for 1) integrating and using evidence-based information and 2) optimising design processes and health care facility performances. It was found that future development of this project should focus on information structuring as foundation of parametric design. The results further indicated that prototype tool design should be integrated in Building Information Modelling systems.