Little is known about the acceptance and incorporation of technological innovations by clinical research sites, a primary entity in the clinical research enterprise in charge of conducting clinical trials. This project explores the adoption of the technological innovations that clinical research sites are presented while conducting trials A qualitative search has been conducted based on case studies about the adoption of two technologies in Danish sites and the input of several actors involved in the process, and with the contribution of innovation theories, this thesis determine the factors involved in influencing technological innovation at the clinical research site and draws a line of recommendations to overcome the obstacles facing technology adoption by the sites.