Synthesising musical instruments and using their digital versions in music production and performance without the need of owning and learning the real instrument is a highly popular demand by the musicians and producers alike. Currently, more and more synthesizers are being developed, decreasing the need for going through a tedious recording process to sample an instrument. As more common and simpler instruments have synthesizers that mimic the real instrument quite well, less known and more complex instruments are waiting in line for a synthesizer that can replace the sample based instrument reproduction. This work focuses on modelling Shamisen using Finite Difference Schemes. The performance of the model is evaluated in perceptual quality and verity tests. While the model does not synthesize a realistic Shamisen sound, the results of the work show the real potential of digitizing the Shamisen using Finite Difference Time Domain methods.