Når kroppen gør ondt - Faktorer med betydning for smerteintensitet ved endometriose. - En kvantitativ spørgeskemaundersøgelse.
Oversat titel
Factors Associated with Pain Intensity in Women with Endometriosis: A Quantitative Questionnaire Study
Forfattere
Schrøder, Camilla ; Hedmark, Camilla Lindberg Juul
Semester
4. semester
Udgivelsesår
2026
Afleveret
2026-09-01
Resumé
Baggrund: Endometriose er en kronisk betændelsestilstand, som ofte medfører langvarige smerter, nedsat livskvalitet og begrænset funktion i hverdagen. Mange kvinder har fortsat smerter, selvom de får både hormonbehandling og eventuel kirurgisk behandling. Tidligere forskning peger på, at psykologiske faktorer, søvnkvalitet og forskellige typer smerter kan hænge sammen med, hvor stærke smerterne opleves. Det er dog stadig uklart, hvor meget disse faktorer hver for sig og samlet kan forklare smerteintensiteten hos kvinder med endometriose. Formål: Denne undersøgelse skulle afdække, i hvilken grad angst, depression, tendens til at overdramatisere smerte (pain catastrophizing), søvnkvalitet og smertekarakteristika kan forklare variation i smerteintensitet hos kvinder med endometriose. Metode: Studiet er et kvantitativt tværsnitsstudie blandt kvinder med klinisk diagnosticeret endometriose, tilknyttet Endometrioseklinikken og Gynækologisk Afdeling på Odense Universitetshospital. Deltagerne udfyldte spørgeskemaer om angst og depression (Hospital Anxiety and Depression Scale, HADS), om måden de tænker og reagerer på smerte (Pain Catastrophizing Scale, PCS), om smertekarakteristika (painDETECT) og om søvnkvalitet (Pittsburgh Sleep Quality Index, PSQI). Sammenhængen mellem de undersøgte faktorer og gennemsnitlig smerteintensitet blev analyseret med multipel lineær regression, suppleret af uafhængige t‑tests til sammenligning af grupper. I den endelige analyse indgik 51 deltagere. Resultater: Den multiple regressionsanalyse viste ingen statistisk signifikante sammenhænge mellem de samlede HADS‑, PCS‑, PSQI‑ og painDETECT‑scores og smerteintensitet. Modellen forklarede 10,9 % af variationen i smerteintensitet (R² = 0,109, p = 0,246), og ingen af de enkelstående faktorer var statistisk signifikante. Der blev heller ikke fundet statistisk signifikante forskelle i smerteintensitet mellem grupper opdelt efter HADS, PCS, PSQI eller painDETECT, selvom der blev observeret tendenser i den forventede retning. Den eneste statistisk signifikante forskel blev fundet mellem kvinder med og uden hormonbehandling, hvor kvinder i hormonbehandling rapporterede højere smerteintensitet (p = 0,023). Konklusion: Undersøgelsen fandt ingen statistisk signifikante sammenhænge mellem de undersøgte psykologiske faktorer, søvnkvalitet, smertekarakteristika og smerteintensitet hos kvinder med endometriose. Resultaterne understøtter, at smerter ved endometriose er komplekse og påvirkes af mange forhold, og at variationen i smerteintensitet ikke kan forklares ud fra de undersøgte faktorer alene.
Background: Endometriosis is a chronic inflammatory condition that often leads to long‑lasting pain, reduced quality of life, and difficulties in everyday functioning. Many women continue to experience pain even when they receive hormone treatment and sometimes surgery. Previous research suggests that psychological factors, sleep quality, and different types of pain may be linked to how intense the pain feels. However, it is still unclear how much these factors, individually and together, can explain pain intensity in women with endometriosis. Objective: This study aimed to examine to what extent anxiety, depression, pain catastrophizing (a tendency to think about pain in a very negative and threatening way), sleep quality, and pain characteristics can explain variation in pain intensity among women with endometriosis. Methods: The study was a quantitative cross‑sectional study including women with clinically diagnosed endometriosis at the Endometriosis Clinic and the Department of Gynecology at Odense University Hospital. Participants completed questionnaires about anxiety and depression (Hospital Anxiety and Depression Scale, HADS), about how they think and react to pain (Pain Catastrophizing Scale, PCS), about pain characteristics (painDETECT), and about sleep quality (Pittsburgh Sleep Quality Index, PSQI). The relationship between the investigated factors and average pain intensity was analyzed using multiple linear regression, supplemented by independent t‑tests to compare groups. A total of 51 participants were included in the final analysis. Results: The multiple regression analysis showed no statistically significant associations between total scores on HADS, PCS, PSQI, painDETECT and pain intensity. The model explained 10.9% of the variation in pain intensity (R² = 0.109, p = 0.246), and none of the individual factors were statistically significant. No statistically significant differences in pain intensity were found between groups based on HADS, PCS, PSQI or painDETECT scores, although trends in the expected direction were observed. The only statistically significant difference was between women with and without hormonal treatment, where women receiving hormonal treatment reported higher pain intensity (p = 0.023). Conclusion: This study found no statistically significant associations between the investigated psychological factors, sleep quality, pain characteristics and pain intensity among women with endometriosis. The findings support that pain in endometriosis is complex and influenced by many different factors, and that variations in pain intensity cannot be explained by the studied factors alone.
[Dette resumé er omskrevet med hjælp fra AI baseret på projektets originale resumé]
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